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KMID : 0525720140190030182
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Journal of Chitin and Chitosan
2014 Volume.19 No. 3 p.182 ~ p.187
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Antibacterial Activity of Chitosan against Antibiotics Resistance Bacteria in Porcine Semen
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Lee Da-Gyung
Kim Dae-Young
Park Jae-Kweon
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Abstract
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Bacteria in porcine semen having resistance on antibiotics decrease the quality and viability of sperms. In the continuing search for potential antibacterial of chitosan with different molecular weight, we have isolated bacterial strain from porcine semen and applied chitosan to address their antibacterial activity. However, definitive evidence for this relationship between different molecular weight chitosan and its antibacterial activity toward some bacterial strains in porcine semen was in lacking. The results showed that no significant synergic effects of chitosan with different molecular weight with antibiotics on bacteria isolated from two different sources of semen were observed. However all chitosan and glucosamine used in this study showed antibacterial activity toward ARB, which showed the resistance especially toward ampicillin and erythromycin. Our data suggest that chitosan can be used as potential therapeutic agents in the treatment of porcine semen that could specifically target antibiotics resistance bacterial cells (ARB).
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KEYWORD
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Porcine semen, Antibiotics Resistance Bacteria, ARB, Antibacterial activity, Chitosan
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